Matthew Thorne was a renowned doctor in Gotham, who turned criminal because it provided him with joy. He established a crime clinic where he provided his medical services and also gave advice on crimes and their performance. He was eventually involved in one of these many crimes and was arrested by Batman and Robin.
Shortly after this, Thorne escaped prison and again opened his crime clinic, but this time he traveled across the country. Batman and Robin learned of his escape and they chased Thorne all the way to California, where Thorne saved Robin's life after he was shot by one of the Crime Doctor's henchmen. In the end, Thorne was betrayed by one of his own men, who shot him in the back, killing the Crime Doctor almost instantly.