A physicist who believed he was destined to become a great conqueror, Alexander the Great took the name of the legendary historical figure for himself and concocted a plan to bend modern society to his own will. Towards this end, he invented a machine whose rays could increase the amount of mass in any object. With this machine, Alexander attempted to blackmail the inhabitants of Manhattan. Several skyscrapers in New York City were made to collapse. The plot was ultimately foiled by Hawkman, and in his battle with the villain, Hawkman stabbed Alexander with a Roman-style trident.
It was believed at the time that Alexander had perished from his injuries. However, he recovered and appeared again later, this time working in concert with Ian Karkull and an assortment of other villains. The scheme Karkull had concocted was thwarted by the efforts of the Justice Society.